Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 13/20 | 0.64 |
| ▸ | EDNRB | P24530 | 12/20 | 0.47 |
| ▸ | CCR9 | P51686 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7949278 | 0.92 | EDNRA (0.64) | EDNRAEDNRBCCR9 | |
| SCHEMBL7013111 | 0.87 | EDNRA (0.80) | EDNRAEDNRB | |
| SCHEMBL7012947 | 0.86 | EDNRA (0.48) | EDNRAEDNRB | |
| SCHEMBL7006427 | 0.84 | EDNRA (0.81) | EDNRAEDNRBCCR9 | |
| SCHEMBL7006902 | 0.82 | EDNRA (0.70) | EDNRAEDNRBCCR9 | |
| SCHEMBL7008278 | 0.82 | EDNRA (0.70) | EDNRAEDNRBCCR9 | |
| SCHEMBL7006905 | 0.82 | EDNRA (0.70) | EDNRAEDNRBCCR9 | |
| SCHEMBL7009309 | 0.82 | EDNRA (0.76) | EDNRAEDNRBCCR9 | |
| SCHEMBL9157048 | 0.82 | EDNRA (0.73) | EDNRAEDNRB | |
| SCHEMBL7099116 | 0.80 | EDNRA (0.63) | EDNRAEDNRBCCR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601386-B1 | Sulphonamides | HOFFMANN LA ROCHE (CH) | 2003-02-05 | — | — | EP | claimed |
| EP-0601386-A1 | Sulphonamides | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-15 | — | — | EP | claimed |
| EP-0601386-B1 | Sulphonamides | HOFFMANN LA ROCHE (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0601386-A1 | Sulphonamides | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-15 | — | — | EP | disclosed |