⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11139485 | 0.75 | — | — | |
| SCHEMBL2112269 | 0.72 | — | — | |
| SCHEMBL16643881 | 0.72 | ALDH1A1 (0.33) | — | |
| SCHEMBL117445 | 0.69 | — | — | |
| SCHEMBL4442419 | 0.69 | — | — | |
| SCHEMBL44558 | 0.69 | — | — | |
| SCHEMBL8310118 | 0.69 | — | — | |
| SCHEMBL2949601 | 0.69 | — | — | |
| SCHEMBL19688908 | 0.67 | — | — | |
| SCHEMBL15571595 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576664-B1 | 1-amido-2-hydroxy-substituted-indanes; suppressing production of tumor necrosis factor | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-06-10 | — | — | US | disclosed |
| EP-1172364-B1 | A process for the preparation of 2-phenyl-imidazo[1,2-A]pyridine-3-acetamides | DINAMITE DIPHARMA S P A IN ABB (IT) | 2003-04-23 | — | — | EP | disclosed |
| US-6384226-B2 | REACTING 2-PHENYL-IMIDAZOLO(1,2-A)PYRIDINE WITH OXALIC ACID ESTER; REDUCTION; AMIDATION | DINAMITE DIPHARMA S.P.A. (IT) | 2002-05-07 | — | — | US | disclosed |
| US-20020019528-A1 | Process for the preparation of 2-phenyl-imidazo [1, 2-a] pyridine-3-acetamides | DINAMITE DIPHARMA S.P.A. | 2002-02-14 | — | — | US | disclosed |
| EP-1172364-A1 | A process for the preparation of 2-phenyl-imidazo[1,2-A]pyridine-3-acetamides | Dinamite Dipharma S.p.A. (in abbreviated form Dipharma S.p.A.) (IT) | 2002-01-16 | — | — | EP | disclosed |
| EP-0790986-B1 | ANILINE DERIVATIVES | ZENECA LTD (GB) | 1999-01-20 | — | — | EP | disclosed |
| EP-0790986-A1 | ANILINE DERIVATIVES | ZENECA LIMITED (GB) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996015118-A1 | ANILINE DERIVATIVES | ZENECA LIMITED (GB) | 1996-05-23 | — | — | WO | disclosed |
| EP-0222022-A1 | PROCESS FOR PRODUCING BETA-LACTAM DERIVATIVES | Otsuka Kagaku Kabushiki Kaisha (JP) | 1987-05-20 | — | — | EP | disclosed |
| US-4286089-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1981-08-25 | — | — | US | disclosed |
| US-4096256-A | ANTIBIOTICS | SMITHKLINE CORPORATION (US) | 1978-06-20 | — | — | US | disclosed |
| US-4093723-A | ANTIBIOTICS | SMITHKLINE CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |
| US-4068073-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4067880-A | SULFOALKYL-OXADIAZOLE THIOLS | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4066761-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |
| US-4059591-A | Ureidoalkyl substituted tetrazole thiol intermediates for preparing cephalosporins | SMITHKLINE CORPORATION (US) | 1977-11-22 | — | — | US | disclosed |
| US-4048311-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4041162-A | ANTIBIOTICS, BACTERICIDES | SMITHKLINE CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |
| US-4034092-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |
| US-4025626-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |