Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3405403 | 0.90 | KDM4E (0.55) | ALDH1A1KDM4ELMNATDP1CYP1A2 | |
| SCHEMBL882663 | 0.84 | CYP1A2 (0.52) | ALDH1A1KDM4ELMNATDP1CYP1A2 | |
| SCHEMBL9461179 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNACYP1A2SMN1; SMN2 | |
| SCHEMBL6694248 | 0.82 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNATDP1CYP1A2 | |
| SCHEMBL3633436 | 0.80 | SMN1; SMN2 (0.50) | ALDH1A1KDM4ELMNASMN1; SMN2POLB | |
| SCHEMBL12868397 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNATDP1CYP1A2 | |
| SCHEMBL31550344 | 0.78 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNATDP1CYP1A2 | |
| SCHEMBL5365414 | 0.78 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNATDP1CYP1A2 | |
| SCHEMBL9461048 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNACYP1A2SMN1; SMN2 | |
| SCHEMBL4595561 | 0.77 | ALDH1A1 (0.56) | ALDH1A1KDM4ELMNATDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353640-B2 | Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE GMBH (DE) | 2003-10-15 | — | — | EP | disclosed |
| EP-0353640-B1 | Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 1995-04-12 | — | — | EP | disclosed |
| US-5186736-A | Pre- and postemergence | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-16 | — | — | US | disclosed |
| US-5053072-A | HETEROCYCLIC N-ACYLSULFONAMIDES, AND THEIR USE AS HERBICIDES OR GROWTH REGULATORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-01 | — | — | US | disclosed |
| EP-0353640-A2 | Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators | Hoechst Schering AgrEvo GmbH (DE) | 1990-02-07 | — | — | EP | disclosed |