Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 2/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7017347 | 0.91 | ALDH1A1 (0.53) | ALDH1A1NPC1RAB9APDE10ANPSR1 | |
| SCHEMBL7020014 | 0.86 | ALDH1A1 (0.51) | ALDH1A1NPC1RAB9AHIF1ANPSR1 | |
| SCHEMBL7020544 | 0.85 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9APDE10ANPSR1 | |
| SCHEMBL7023775 | 0.85 | ALDH1A1 (0.55) | ALDH1A1NPC1RAB9ANPSR1KMT2A | |
| SCHEMBL7017651 | 0.84 | ALDH1A1 (0.51) | ALDH1A1NPC1RAB9APDE10ANPSR1 | |
| SCHEMBL7023691 | 0.84 | ALDH1A1 (0.54) | ALDH1A1NPC1RAB9ANPSR1KMT2A | |
| SCHEMBL7016929 | 0.82 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9APDE10ANPSR1 | |
| SCHEMBL7025842 | 0.82 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9APDE10ANPSR1 | |
| SCHEMBL7019250 | 0.82 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9AHIF1APDE10A | |
| SCHEMBL7016751 | 0.82 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9APDE10ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |