Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 11/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | CASR | P41180 | 2/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014708 | 0.83 | ELANE (0.49) | ELANEPARP1CASRPIK3CDCTRB1 | |
| SCHEMBL7011912 | 0.80 | ELANE (0.46) | ELANEPARP1CASRPIK3CDCTRB1 | |
| SCHEMBL2069228 | 0.80 | ELANE (0.49) | SMN1; SMN2ELANE | |
| SCHEMBL10173803 | 0.80 | PIK3CD (0.50) | ELANEPARP1CASRPIK3CD | |
| SCHEMBL16664255 | 0.78 | PIK3CD (0.43) | ELANEPARP1CASRPIK3CDCTRB1 | |
| SCHEMBL4402541 | 0.77 | ESR2 (0.46) | SMN1; SMN2ELANEPARP1PIK3CD | |
| SCHEMBL1161604 | 0.76 | PIK3CD (0.50) | ELANEPARP1CASRPIK3CD | |
| SCHEMBL28116231 | 0.75 | PIK3CD (0.43) | ELANEPARP1CASRPIK3CD | |
| SCHEMBL2611507 | 0.74 | KDM4E (0.64) | SMN1; SMN2 | |
| SCHEMBL30879806 | 0.74 | KDM4E (0.64) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-5753664-A | ANTITUMOR AGENTS, PYRIMIDONES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |