Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011506 | 0.93 | MEN1 (0.55) | PTGDR2MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7013156 | 0.90 | DAO (0.50) | PTGDR2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7101327 | 0.90 | MEN1 (0.60) | PTGDR2MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7017586 | 0.90 | MEN1 (0.57) | PTGDR2MEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL7015787 | 0.89 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2NPC1MAPT | |
| SCHEMBL7014429 | 0.89 | MEN1 (0.54) | MEN1KMT2ADRD2TBXA2RSMN1; SMN2 | |
| SCHEMBL7018370 | 0.88 | MEN1 (0.50) | PTGDR2MEN1KMT2ADRD2TBXA2R | |
| SCHEMBL7015657 | 0.88 | TP53 (0.52) | MEN1KMT2ASMN1; SMN2RAB9AMAPT | |
| SCHEMBL7013147 | 0.88 | MEN1 (0.50) | PTGDR2MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7010770 | 0.87 | MEN1 (0.47) | PTGDR2MEN1KMT2ADRD2TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-5753664-A | ANTITUMOR AGENTS, PYRIMIDONES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |