Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.70 |
| ▸ | HTT | P42858 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | BRD4 | O60885 | 1/20 | 0.70 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.63 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7824014 | 0.86 | DRD3 (0.84) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL10738656 | 0.86 | DRD3 (0.84) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| Pefloxacin SCHEMBL34292 | 0.86 | DRD3 (1.00) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| Pefloxacin SCHEMBL28251251 | 0.86 | DRD3 (1.00) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| Pefloxacin SCHEMBL29351730 | 0.86 | DRD3 (1.00) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL11022977 | 0.85 | DRD3 (0.83) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| Pefloxacin SCHEMBL10911017 | 0.85 | DRD3 (0.98) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL21828810 | 0.85 | MEN1 (0.79) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL22698592 | 0.85 | HSD17B10 (0.84) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL7404567 | 0.85 | DRD3 (0.52) | DRD3HSD17B10KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614664-B2 | Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5889009-A | ADMINISTERING 1,7-DISUBSTITUTED-4-OX-3-(QUINOLINECARBOXYLIC ACID OR NAPHTHYRIDINECARBOXYLIC ACID) | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-30 | — | — | US | disclosed |
| EP-0614664-B1 | Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-09-16 | — | — | EP | disclosed |
| US-5703081-A | CELL ADHESION INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| US-5519024-A | CELL ADHESION INHIBITOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
| CN-1099029-A | Carbostyril carboxylic acid derivatives, its preparation and purposes | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-02-22 | — | — | CN | disclosed |
| EP-0614664-A1 | Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-09-14 | — | — | EP | disclosed |