Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.32 |
| ▸ | FDPS | P14324 | 11/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26113457 | 0.98 | TSHR (0.38) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL26113601 | 0.98 | TSHR (0.38) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL3481656 | 0.95 | — | — | |
| SCHEMBL6057054 | 0.90 | TSHR (0.37) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL28616634 | 0.87 | TSHR (0.42) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL6057156 | 0.87 | TSHR (0.42) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL7056923 | 0.87 | TSHR (0.42) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL27943194 | 0.87 | TSHR (0.35) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL29240685 | 0.84 | CES2 (0.35) | THRBCES2 | |
| SCHEMBL703720 | 0.84 | TSHR (0.32) | TSHRTHRBSMPD1FDPSGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425350-A1 | SILICA-COATED MIXED CRYSTAL OXIDE PARTICLE, PRODUCTION PROCESS THEREOF AND COSMETIC MATERIAL USING THE SAME | SHOWA DENKO KABUSHIKI KAISHA (JP) | 2004-06-09 | — | — | EP | disclosed |
| EP-1392773-A1 | ROOM-TEMPERATURE-CURABLE SILICONE RUBBER COMPOSITION | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 2004-03-03 | — | — | EP | disclosed |
| WO-2003025071-A1 | SILICA-COATED MIXED CRYSTAL OXIDE PARTICLE, PRODUCTION PROCESS THEREOF AND COSMETIC MATERIAL USING THE SAME | SHOWA DENKO K.K. (JP) | 2003-03-27 | — | — | WO | disclosed |
| WO-2002096993-A1 | ROOM-TEMPERATURE-CURABLE SILICONE RUBBER COMPOSITION | DOW CORNING TORAY SILICONE CO.,LTD. (JP) | 2002-12-05 | — | — | WO | disclosed |