Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | MGAM | O43451 | 3/20 | 0.31 |
| ▸ | SI | P14410 | 3/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5379670 | 0.92 | LTA4H (0.41) | NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL4630511 | 0.88 | KCNA3 (0.41) | KCNA3NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7648797 | 0.87 | SMN1; SMN2 (0.51) | KCNA3NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL10785918 | 0.85 | KCNA3 (0.43) | KCNA3MAPTTAAR1ALDH1A1RECQL | |
| SCHEMBL5026563 | 0.85 | KCNA3 (0.43) | KCNA3GAAHDAC3HDAC4HDAC1 | |
| SCHEMBL28073630 | 0.85 | KCNA3 (0.43) | KCNA3GAAHDAC3HDAC4HDAC1 | |
| SCHEMBL3227774 | 0.85 | KCNA3 (0.43) | KCNA3GAAHDAC3HDAC4HDAC1 | |
| SCHEMBL8140756 | 0.82 | NPC1 (0.47) | KCNA3NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5385658 | 0.81 | LTA4H (0.44) | KCNA3 | |
| SCHEMBL1006143 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5099030-A | Phenols or phenolic ethers | THE PROCTER & GAMBLE COMPANY (US) | 1992-03-24 | — | — | US | claimed |
| CN-111205282-B | ER protein modulators and uses thereof | 上海科技大学 | 2023-12-01 | — | — | CN | disclosed |
| CN-117050002-A | Novel compounds having estrogen receptor alpha degrading activity and uses thereof | 冰洲石生物科技公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-113164409-B | Compounds having estrogen receptor alpha degrading activity and uses thereof | 冰洲石生物科技公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-108727407-B | Novel benzodiazepine derivatives | 伊缪诺金公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-113164409-A | Novel compounds having estrogen receptor alpha-degrading activity and uses thereof | 冰洲石生物科技公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-112566666-A | Compounds targeting anti-cancer nuclear hormone receptors | 努瓦申生物公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-111205282-A | ER protein modulators and uses thereof | 上海科技大学 | 2020-05-29 | — | — | CN | disclosed |
| CN-105198908-B | Novel benzodiazepine derivatives | 伊缪诺金公司 | 2019-12-24 | — | — | CN | disclosed |
| EP-1368324-A1 | QUINAZOLINES AS MMP-13 INHIBITORS | Warner-Lambert Company LLC (US) | 2003-12-10 | — | — | EP | disclosed |
| EP-1235831-A2 | NEW OXABISPIDINE COMPOUNDS USEFUL IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | AstraZeneca AB (SE) | 2002-09-04 | — | — | EP | disclosed |
| WO-2002064572-A1 | QUINAZOLINES AS MMP-13 INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | disclosed |
| WO-2001028992-A2 | NEW OXABISPIDINE COMPOUNDS USEFUL IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2001-04-26 | — | — | WO | disclosed |
| EP-0282127-B1 | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them | PROCTER & GAMBLE (US) | 1994-02-02 | — | — | EP | disclosed |
| US-5099030-A | Phenols or phenolic ethers | THE PROCTER & GAMBLE COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-5045565-A | Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain | THE PROCTER & GAMBLE COMPANY (US) | 1991-09-03 | — | — | US | disclosed |
| EP-0282127-A2 | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them | THE PROCTER & GAMBLE COMPANY (US) | 1988-09-14 | — | — | EP | disclosed |