Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 19/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7015839 | 0.99 | BDKRB2 (0.74) | BDKRB2 | |
| SCHEMBL7014752 | 0.93 | BDKRB2 (0.63) | BDKRB2 | |
| SCHEMBL7012572 | 0.92 | BDKRB2 (0.66) | BDKRB2 | |
| SCHEMBL7010161 | 0.91 | BDKRB2 (0.61) | BDKRB2 | |
| SCHEMBL7015387 | 0.91 | BDKRB2 (0.61) | BDKRB2 | |
| SCHEMBL7016569 | 0.91 | BDKRB2 (0.60) | BDKRB2 | |
| SCHEMBL7017869 | 0.90 | BDKRB2 (0.64) | BDKRB2 | |
| SCHEMBL7012550 | 0.90 | BDKRB2 (0.60) | BDKRB2 | |
| SCHEMBL7012380 | 0.89 | BDKRB2 (0.64) | BDKRB2 | |
| SCHEMBL7011669 | 0.89 | BDKRB2 (0.61) | BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861243-B1 | HETEROCYCLIC COMPOUNDS AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-11-12 | — | — | EP | disclosed |
| US-6344462-B1 | Heterocyclic compounds as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-05 | — | — | US | disclosed |
| US-6100284-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-08 | — | — | US | disclosed |
| US-6008229-A | TREATING ALLERGY, INFLAMMATION, AUTOIMMUNE DISEASE, SHOCK, PAIN | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |