Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 5/20 | 0.47 |
| ▸ | HTR7 | P34969 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011681 | 0.92 | HPGD (0.48) | ALDH1A1GAAMEN1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL7722346 | 0.91 | HPGD (0.48) | ALDH1A1GAAMEN1KMT2AHPGD | |
| SCHEMBL7013085 | 0.88 | GAA (0.58) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL7013064 | 0.86 | HTR1A (0.53) | ALDH1A1GAAMEN1KMT2AHPGD | |
| SCHEMBL7007308 | 0.84 | HTR1A (0.61) | ALDH1A1HPGDHTR1AHTR7ADRA1D | |
| SCHEMBL7014998 | 0.84 | HTR1A (0.61) | GAAHTR1AHTR7MAPK1KDM4E | |
| SCHEMBL7012098 | 0.81 | RXFP1 (0.54) | ALDH1A1GAAMEN1KMT2AHPGD | |
| SCHEMBL7012057 | 0.78 | HTR1A (0.61) | GAAHPGDPOLBHTR1AHTR7 | |
| SCHEMBL7014563 | 0.78 | HTR1A (0.53) | HPGDPOLBHTR1AHTR7ADRA1D | |
| SCHEMBL7007932 | 0.78 | HTR1A (0.60) | GAAHPGDPOLBHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988306-B1 | 3-SUBSTITUTED 3,4 DIHYDRO-THIENO 2, 3-D]PYRIMIDINE DERIVATIVES AND PRODUCTION AND USE OF THE SAME | ABBOTT GMBH & CO KG (DE) | 2003-07-09 | — | — | EP | disclosed |
| US-6387912-B1 | STROKE THERAPY | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-14 | — | — | US | disclosed |
| US-6159962-A | 3-substituted 3,4-dihydro-thieno[2,3-D]pyrimidine derivatives and production and use of the same | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-12 | — | — | US | disclosed |