Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | JAK3 | P52333 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | NPY1R | P25929 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021884 | 0.90 | AKT1 (0.35) | AKT1MAPTJAK3JAK2JAK1 | |
| SCHEMBL7014606 | 0.85 | NPY1R (0.32) | NPY1R | |
| SCHEMBL7012282 | 0.85 | HTR2C (0.38) | MAPTMEN1KMT2AALDH1A1NPY1R | |
| SCHEMBL7022375 | 0.84 | NPY1R (0.36) | AKT1ALDH1A1NPY1RSMN1; SMN2LMNA | |
| SCHEMBL7022451 | 0.84 | NPY1R (0.36) | MAPTNPY1RSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7016803 | 0.84 | MRGPRX4 (0.41) | AKT1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7010773 | 0.84 | NPY1R (0.35) | MEN1KMT2AALDH1A1NPY1RSMN1; SMN2 | |
| SCHEMBL7018835 | 0.82 | NPY1R (0.36) | NPY1R | |
| SCHEMBL7018031 | 0.81 | TSHR (0.35) | ALDH1A1NPY1RSMN1; SMN2LMNA | |
| SCHEMBL7016610 | 0.79 | NPY1R (0.35) | MAPTNPY1RSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |