Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26847970 | 0.81 | PPARD (0.33) | PPARDKDM4EMMP2THRBMAPK1 | |
| SCHEMBL5290013 | 0.79 | GABBR2 (0.38) | PPARDMMP2 | |
| SCHEMBL28291034 | 0.79 | PPARD (0.32) | PPARDTSHR | |
| Phosphoric Acid SCHEMBL10727717 | 0.78 | PPARD (0.37) | PPARDKDM4EMMP2THRBMAPK1 | |
| SCHEMBL7014931 | 0.76 | TSHR (0.46) | PPARDTSHR | |
| SCHEMBL28357081 | 0.76 | TSHR (0.35) | TSHR | |
| SCHEMBL27687703 | 0.76 | PPARD (0.39) | PPARDTSHR | |
| SCHEMBL1577815 | 0.75 | TSHR (0.41) | TSHR | |
| SCHEMBL28291033 | 0.73 | TSHR (0.33) | TSHR | |
| SCHEMBL31393230 | 0.73 | PPARD (0.34) | PPARDKDM4EMMP2THRBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1360222-A1 | ORGANOPOLYSILOXANES CONTAINING PHOSPHONIC GROUPS, METHODS FOR THE PRODUCTION AND USE THEREOF | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002055587-A1 | ORGANOPOLYSILOXANES CONTAINING PHOSPHONIC GROUPS, METHODS FOR THE PRODUCTION AND USE THEREOF | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2002-07-18 | — | — | WO | disclosed |