Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21750029 | 0.84 | DPP4 (0.56) | DPP4ALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL29469371 | 0.83 | DPP4 (0.54) | DPP4ALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL913406 | 0.83 | DPP4 (0.54) | DPP4ALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL2450664 | 0.83 | THRB (0.40) | DPP4ALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL1398085 | 0.83 | KMT2A (0.38) | DPP4ALDH1A1KDM4EHSD17B10POLB | |
| 2,3,6-Trichlorobenzoic Acid SCHEMBL29365114 | 0.81 | DPP4 (0.62) | DPP4ALDH1A1KDM4EHSD17B10TSHR | |
| 2,3,6-Trichlorobenzoic Acid SCHEMBL117071 | 0.81 | DPP4 (0.62) | DPP4ALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL3574434 | 0.81 | DPP4 (0.47) | DPP4ALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL4849227 | 0.80 | MAPT (0.48) | ALDH1A1HSD17B10POLBMAPTTDP1 | |
| 2,3,6-Trichlorobenzoic Acid SCHEMBL10490012 | 0.79 | DPP4 (0.60) | DPP4ALDH1A1KDM4EHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |
| EP-0373531-A1 | Novel pyridobenzoxazine derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1990-06-20 | — | — | EP | disclosed |
| US-4272531-A | ENZYME INHIBITORS | SMITHKLINE CORPORATION (US) | 1981-06-09 | — | — | US | disclosed |
| US-4146718-A | BLOOD PLATELET ANTIAGGREGATIVE AGENT | BRISTOL-MYERS COMPANY (US) | 1979-03-27 | — | — | US | disclosed |