Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5413005 | 0.85 | MAPT (0.51) | MAPTALDH1A1MAPK1TDP1KMT2A | |
| SCHEMBL5410532 | 0.73 | MAPT (0.46) | MAPTALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL5402116 | 0.70 | MAPT (0.47) | MAPTALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL5408444 | 0.69 | MEN1 (0.58) | KMT2AMEN1LMNAPDE5A | |
| SCHEMBL5412840 | 0.69 | MAPT (0.46) | MAPTALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL5409577 | 0.69 | MAPT (0.44) | MAPTALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL5408518 | 0.69 | GPR55 (0.48) | MAPTALDH1A1MAPK1TDP1KMT2A | |
| SCHEMBL5407504 | 0.69 | MAPT (0.47) | MAPTALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL5408026 | 0.69 | MAPT (0.51) | MAPTALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL7012571 | 0.68 | MEN1 (0.52) | MAPTALDH1A1MAPK1KMT2APTPN12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294729-A1 | 2-AMINOALKYL-THIENO[2,3-D]PYRIMIDINES | MERCK PATENT GmbH (DE) | 2003-03-26 | — | — | EP | claimed |
| WO-2002000664-A1 | 2-AMINOALKYL-THIENO[2,3-D]PYRIMIDINES | MERCK PATENT GMBH (DE) | 2002-01-03 | — | — | WO | claimed |