Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 7/20 | 0.41 |
| ▸ | ACHE | P22303 | 5/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014967 | 0.90 | PTGIR (0.45) | PTGIRBCHEACHEMAOBNPC1 | |
| SCHEMBL7016524 | 0.86 | PTGIR (0.46) | PTGIRBCHEACHEMAOBNPC1 | |
| SCHEMBL7015161 | 0.82 | PTGIR (0.47) | PTGIRBCHEACHEMAOBNPC1 | |
| SCHEMBL7013649 | 0.81 | PTGIR (0.44) | PTGIRBCHEACHEMAOBNPC1 | |
| SCHEMBL7020413 | 0.80 | PTGIR (0.48) | PTGIRBCHEACHEMAOBNPC1 | |
| SCHEMBL7016269 | 0.80 | PTGIR (0.45) | PTGIRBCHEACHEMAOBNPC1 | |
| SCHEMBL7013691 | 0.80 | BCHE (0.50) | PTGIRBCHEACHEMAOBNPC1 | |
| SCHEMBL7015029 | 0.80 | SMN1; SMN2 (0.47) | MAOBNPC1ALDH1A1TSHRRAB9A | |
| SCHEMBL7013595 | 0.79 | TUBB4A (0.45) | NPC1ALDH1A1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL21268347 | 0.76 | MAPKAPK2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |