Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.54 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 9/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4800127 | 0.96 | RAB9A (0.59) | RAB9AHPGDLMNAEPHX2NPC1 | |
| SCHEMBL2533532 | 0.90 | HPGD (0.57) | RAB9AHPGDLMNANPC1SMN1; SMN2 | |
| SCHEMBL1419617 | 0.84 | MAPK1 (0.54) | RAB9AHPGDLMNANPC1SMN1; SMN2 | |
| SCHEMBL8600999 | 0.82 | RAB9A (0.67) | RAB9AHPGDLMNAEPHX2NPC1 | |
| SCHEMBL8076542 | 0.81 | RAB9A (0.65) | RAB9AHPGDLMNAEPHX2NPC1 | |
| SCHEMBL7995030 | 0.81 | RAB9A (0.65) | RAB9AHPGDLMNAEPHX2NPC1 | |
| SCHEMBL1837292 | 0.81 | RAB9A (0.65) | RAB9AHPGDLMNAEPHX2NPC1 | |
| SCHEMBL10599124 | 0.81 | RAB9A (0.65) | RAB9AHPGDLMNAEPHX2NPC1 | |
| SCHEMBL8600460 | 0.81 | RAB9A (0.65) | RAB9AHPGDLMNAEPHX2NPC1 | |
| SCHEMBL1834100 | 0.81 | RAB9A (0.65) | RAB9AHPGDLMNAEPHX2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |