Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7013486 | 0.90 | MEN1 (0.45) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL7008893 | 0.90 | MEN1 (0.45) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL7010770 | 0.89 | MEN1 (0.47) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL7014705 | 0.87 | MEN1 (0.43) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL7011506 | 0.87 | MEN1 (0.55) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL7016212 | 0.86 | MEN1 (0.42) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL7013156 | 0.86 | DAO (0.50) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL7017431 | 0.86 | MEN1 (0.52) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL7011070 | 0.86 | MEN1 (0.52) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL7012383 | 0.86 | KCNH2 (0.51) | MEN1KMT2AKCNH2HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |