SCHEMBL7015550

SCHEMBL7015550

Cc1cc(=O)n2cccc(OCc3c(Cl)ccc(S(=O)(=O)N4CCC[C@H]4C(=O)NCCCNC(=O)c4ccc(C(N)=NO)cc4)c3Cl)c2n1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 2/20 0.65
RORC P51449 18/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7014798 0.94 BDKRB2 (0.63) BDKRB2RORC
SCHEMBL7018765 0.93 BDKRB2 (0.75) BDKRB2RORC
SCHEMBL7715503 0.92 BDKRB2 (0.73) BDKRB2RORC
SCHEMBL7014894 0.91 BDKRB2 (0.62) BDKRB2RORC
SCHEMBL7719630 0.91 BDKRB2 (0.62) BDKRB2RORC
SCHEMBL7012388 0.91 BDKRB2 (0.62) BDKRB2RORC
SCHEMBL7719626 0.91 BDKRB2 (0.62) BDKRB2RORC
SCHEMBL7012391 0.91 BDKRB2 (0.62) BDKRB2RORC
SCHEMBL7014628 0.90 BDKRB2 (0.61) BDKRB2RORC
SCHEMBL7014632 0.90 BDKRB2 (0.61) BDKRB2RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0991650-B1 NOVEL N-BENZENESULPHONYL-L-PROLINE COMPOUNDS, PREPARATION METHOD AND USE IN THERAPY FOURNIER IND & SANTE (FR) 2003-09-10 EP disclosed
EP-0991650-A1 NOVEL N-BENZENESULPHONYL-L-PROLINE COMPOUNDS, PREPARATION METHOD AND USE IN THERAPY FOURNIER INDUSTRIE ET SANTE (FR) 2000-04-12 EP disclosed
WO-1999000387-A1 NOVEL N-BENZENESULPHONYL-L-PROLINE COMPOUNDS, PREPARATION METHOD AND USE IN THERAPY FOURNIER INDUSTRIE ET SANTE (FR) 1999-01-07 WO disclosed