SCHEMBL7015572

SCHEMBL7015572

CC(C)[C@H](N)C(=O)OC(=O)C(=O)OC(=O)[C@@H](N)C(C)C

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.48
DPP4 P27487 2/20 0.35
FAP Q12884 1/20 0.35
DPP8 Q6V1X1 1/20 0.35
DPP9 Q86TI2 1/20 0.35
DPP7 Q9UHL4 1/20 0.35
LAP3 P28838 1/20 0.35
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31
SLC1A1 P43005 1/20 0.31
PSMB5 P28074 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL288204 0.89 SLC7A5 (0.52) SLC7A5DPP4FAPDPP8DPP9
SCHEMBL10530419 0.89 SLC7A5 (0.52) SLC7A5DPP4FAPDPP8DPP9
SCHEMBL29388526 0.88 SLC7A5 (0.48) SLC7A5DPP4FAPDPP8DPP9
SCHEMBL8417265 0.86 SLC7A5 (0.41) SLC7A5DPP4FAPDPP8DPP9
SCHEMBL29269089 0.82 SLC7A5 (0.46) SLC7A5DPP4FAPDPP8DPP9
SCHEMBL28911829 0.82 SLC7A5 (0.46) SLC7A5DPP4FAPDPP8DPP9
SCHEMBL756027 0.82 SLC7A5 (0.46) SLC7A5DPP4FAPDPP8DPP9
SCHEMBL10710883 0.82 SLC7A5 (0.46) SLC7A5DPP4FAPDPP8DPP9
SCHEMBL1615114 0.82 SLC7A5 (0.46) SLC7A5DPP4FAPDPP8DPP9
SCHEMBL229820 0.82 SLC7A5 (0.46) SLC7A5DPP4FAPDPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030232860-A1 Medicine comprising dicyanopyridine derivative ASTELLAS PHARMA INC. (JP) 2003-12-18 US disclosed
EP-1302463-A1 MEDICINE COMPRISING DICYANOPYRIDINE DERIVATIVE YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 2003-04-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232860-A1 Medicine comprising dicyanopyridine derivative KCNN3, KCNN2, KCNN1 SLC7A5 1295/4885DPP4 584/4885FAP 2017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.