Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.50 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10861606 | 0.90 | LMNA (0.82) | LMNAKMT2AMEN1ALDH1A1DRD3 | |
| SCHEMBL10776491 | 0.87 | LMNA (0.80) | LMNAKMT2AMEN1ALDH1A1DRD3 | |
| Difloxacin SCHEMBL29695838 | 0.86 | LMNA (1.00) | LMNAKMT2AMEN1ALDH1A1DRD3 | |
| Difloxacin SCHEMBL148765 | 0.86 | LMNA (1.00) | LMNAKMT2AMEN1ALDH1A1DRD3 | |
| SCHEMBL9787515 | 0.85 | LMNA (0.86) | LMNAKMT2AMEN1ALDH1A1DRD3 | |
| Difloxacin SCHEMBL203110 | 0.85 | LMNA (0.98) | LMNAKMT2AMEN1ALDH1A1DRD3 | |
| SCHEMBL10531040 | 0.85 | LMNA (0.86) | LMNAKMT2AMEN1ALDH1A1DRD3 | |
| SCHEMBL10862888 | 0.85 | KMT2A (0.76) | LMNAKMT2AMEN1ALDH1A1DRD3 | |
| SCHEMBL10866307 | 0.85 | LMNA (0.76) | LMNAKMT2AMEN1ALDH1A1DRD3 | |
| Difloxacin SCHEMBL27973383 | 0.84 | LMNA (0.96) | LMNAKMT2AMEN1ALDH1A1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313708-A1 | QUINOLINE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | CHIRON CORPORATION (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018345-A1 | QUINOLINE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | CHIRON CORPORATION (US) | 2002-03-07 | — | — | WO | disclosed |