Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012803 | 0.89 | KEAP1 (0.46) | KEAP1NFE2L2MAPTMEN1KMT2A | |
| SCHEMBL4458375 | 0.89 | KEAP1 (0.46) | KEAP1NFE2L2MAPTMEN1KMT2A | |
| SCHEMBL29457327 | 0.89 | KEAP1 (0.46) | KEAP1NFE2L2MAPTMEN1KMT2A | |
| SCHEMBL7172244 | 0.89 | KEAP1 (0.46) | KEAP1NFE2L2MAPTMEN1KMT2A | |
| SCHEMBL29733883 | 0.89 | KEAP1 (0.46) | KEAP1NFE2L2MAPTMEN1KMT2A | |
| SCHEMBL5781037 | 0.81 | KEAP1 (0.50) | KEAP1NFE2L2 | |
| SCHEMBL21174043 | 0.81 | KEAP1 (0.50) | KEAP1NFE2L2 | |
| SCHEMBL5781044 | 0.81 | KEAP1 (0.50) | KEAP1NFE2L2 | |
| SCHEMBL5160108 | 0.81 | KEAP1 (0.58) | KEAP1NFE2L2MAPTLMNA | |
| SCHEMBL21309261 | 0.81 | KEAP1 (0.46) | KEAP1NFE2L2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341781-A1 | ANTIMICROBIAL QUINOLONES | THE PROCTER & GAMBLE COMPANY (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002048138-A1 | ANTIMICROBIAL QUINOLONES | THE PROCTER & GAMBLE COMPANY (US) | 2002-06-20 | — | — | WO | disclosed |