Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 20/20 | 0.60 |
| ▸ | HTR1D | P28221 | 16/20 | 0.60 |
| ▸ | HTR1B | P28222 | 15/20 | 0.60 |
| ▸ | HTR1A | P08908 | 12/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR1E | P28566 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831931 | 0.85 | HTR1F (0.60) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7016273 | 0.81 | HTR1F (0.62) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7018777 | 0.80 | HTR1F (0.63) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7018204 | 0.80 | HTR1F (0.60) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7017382 | 0.78 | HTR1F (0.58) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7018965 | 0.76 | HTR1F (0.62) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7009081 | 0.75 | HTR1F (0.71) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7007941 | 0.75 | HTR1F (1.00) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7006910 | 0.75 | HTR1F (1.00) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL7011996 | 0.73 | HTR1F (1.00) | HTR1FHTR1DHTR1BHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089993-B1 | 5-HT1F AGONISTS | LILLY CO ELI (US) | 2003-10-22 | — | — | EP | disclosed |
| US-6358972-B1 | FOR THERAPY OF MIGRAINE | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |