⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13708285 | 0.87 | — | — | |
| SCHEMBL7012615 | 0.78 | KDM4E (0.45) | — | |
| SCHEMBL13708265 | 0.77 | — | — | |
| SCHEMBL13708251 | 0.77 | — | — | |
| SCHEMBL13708255 | 0.76 | — | — | |
| SCHEMBL13708263 | 0.76 | — | — | |
| SCHEMBL13708287 | 0.75 | — | — | |
| SCHEMBL13708257 | 0.74 | — | — | |
| SCHEMBL13708252 | 0.73 | — | — | |
| SCHEMBL13708256 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1048651-B1 | NITROGEN-CONTAINING TETRACYCLIC COMPOUNDS | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-05-14 | — | — | EP | disclosed |
| US-6281355-B1 | Nitrogen-containing tetracyclic compounds | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2001-08-28 | — | — | US | disclosed |
| EP-1048651-A1 | NITROGEN-CONTAINING TETRACYCLIC COMPOUNDS | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2000-11-02 | — | — | EP | disclosed |