Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016751 | 0.91 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9APDE10A | |
| SCHEMBL7022053 | 0.91 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9ALMNACCKBR | |
| SCHEMBL7024862 | 0.89 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9ALMNACCKBR | |
| SCHEMBL7020552 | 0.89 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9ALMNACCKBR | |
| SCHEMBL7020823 | 0.87 | ALDH1A1 (0.43) | ALDH1A1NPC1RAB9ALMNACCKBR | |
| SCHEMBL7018493 | 0.85 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9ALMNACCKBR | |
| SCHEMBL7020586 | 0.85 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9ALMNACCKBR | |
| SCHEMBL7015471 | 0.85 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9ALMNACCKBR | |
| SCHEMBL7025087 | 0.85 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9ALMNACCKBR | |
| SCHEMBL7023046 | 0.85 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9ALMNACCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |