Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TOP2A | P11388 | 9/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 9/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010134 | 0.93 | DRD3 (0.48) | KDM4EALDH1A1TOP2ATOP2BDRD3 | |
| SCHEMBL7011144 | 0.91 | KDM4E (0.62) | KDM4EALDH1A1TOP2ATOP2BDRD3 | |
| SCHEMBL7013895 | 0.90 | KDM4E (0.55) | KDM4EALDH1A1TOP2ATOP2BDRD3 | |
| SCHEMBL7009430 | 0.88 | KDM4E (0.53) | KDM4EALDH1A1TOP2ATOP2BDRD3 | |
| SCHEMBL7004815 | 0.88 | KDM4E (0.52) | KDM4EALDH1A1TOP2ATOP2BDRD3 | |
| SCHEMBL7012150 | 0.86 | KDM4E (0.46) | KDM4EALDH1A1TOP2ATOP2BHPGD | |
| SCHEMBL7011715 | 0.84 | TOP2A (0.60) | KDM4EALDH1A1TOP2ATOP2BHPGD | |
| SCHEMBL7017563 | 0.84 | KDM4E (0.52) | KDM4EALDH1A1TOP2ATOP2BDRD3 | |
| SCHEMBL7004318 | 0.83 | LMNA (0.52) | KDM4EALDH1A1TOP2ATOP2BHPGD | |
| SCHEMBL8319527 | 0.83 | TOP2A (0.46) | KDM4EALDH1A1TOP2ATOP2BHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |