Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4412173 | 0.95 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1PKMTAAR1CPB2 | |
| SCHEMBL31303986 | 0.88 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1PKMTAAR1HIF1A | |
| SCHEMBL14696607 | 0.84 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1PKMTAAR1HIF1A | |
| SCHEMBL27972864 | 0.84 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1PKMTAAR1EGFR | |
| Trifluoroacetic Acid SCHEMBL29174401 | 0.83 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1PKMTAAR1CPB2 | |
| SCHEMBL28281549 | 0.83 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1PKMTAAR1EGFR | |
| SCHEMBL28281482 | 0.83 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1PKMTAAR1EGFR | |
| SCHEMBL9730065 | 0.83 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1PKMTAAR1CPB2 | |
| SCHEMBL28813221 | 0.82 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1PKMTAAR1EGFR | |
| SCHEMBL19406117 | 0.82 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1PKMTAAR1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1026170-B1 | Erythromycin derivatives, their preparation and use as medicaments | AVENTIS PHARMA SA (FR) | 2003-01-15 | — | — | EP | disclosed |
| US-6313101-B1 | ANTIBIOTICS | AVENTIS PHARMA S.A. (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-1026170-A1 | Erythromycin derivatives, their preparation and use as medicaments | HOECHST MARION ROUSSEL (FR) | 2000-08-09 | — | — | EP | disclosed |