Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 12/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 1.00 |
| ▸ | ADORA2B | P29275 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.75 |
| ▸ | MAPT | P10636 | 5/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.75 |
| ▸ | MEN1 | O00255 | 5/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.75 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.75 |
| ▸ | HTT | P42858 | 3/20 | 0.75 |
| ▸ | HPGD | P15428 | 3/20 | 0.75 |
| ▸ | GAA | P10253 | 1/20 | 0.75 |
| ▸ | STAT6 | P42226 | 1/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6252924 | 0.83 | ALDH1A1 (0.81) | ADORA1ADORA3ADORA2BALDH1A1MAPT | |
| SCHEMBL5040253 | 0.82 | ALDH1A1 (0.85) | ADORA1ADORA3ADORA2BALDH1A1MAPT | |
| SCHEMBL6441319 | 0.82 | ADORA1 (0.69) | ADORA1ADORA3ADORA2BALDH1A1MAPT | |
| SCHEMBL13913670 | 0.81 | ADORA1 (1.00) | ADORA1ADORA3ADORA2BALDH1A1MEN1 | |
| SCHEMBL6442951 | 0.81 | KDM4E (0.68) | ADORA1ADORA3ADORA2BALDH1A1MAPT | |
| SCHEMBL1026852 | 0.80 | ALDH1A1 (0.71) | ADORA1ADORA3ADORA2BALDH1A1MAPT | |
| SCHEMBL1028936 | 0.80 | ALDH1A1 (0.81) | ADORA1ADORA3ADORA2BALDH1A1MAPT | |
| SCHEMBL1027093 | 0.79 | ALDH1A1 (0.69) | ADORA1ADORA3ADORA2BALDH1A1MAPT | |
| SCHEMBL1028323 | 0.79 | ALDH1A1 (0.80) | ADORA1ADORA3ADORA2BALDH1A1MAPT | |
| SCHEMBL1028666 | 0.79 | ALDH1A1 (0.80) | ADORA1ADORA3ADORA2BALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1302463-A1 | MEDICINE COMPRISING DICYANOPYRIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2003-04-16 | — | — | EP | disclosed |