Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014690 | 0.85 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL7010457 | 0.80 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL7009867 | 0.80 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL7013213 | 0.79 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL7013722 | 0.78 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL7014100 | 0.74 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9089049 | 0.74 | PPARG (0.44) | AGTR1AGTR2 | |
| SCHEMBL7008117 | 0.72 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL7018967 | 0.72 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL7014580 | 0.72 | PDE4A (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520423-B1 | Heterocyclic compounds, their production and use as angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-14 | — | — | EP | disclosed |
| US-6100252-A | SPECIFIED COMPOUNDS INCLUDING METHYL 2-BUTYL-1-((2'-(2-OXO-3H-1,2,3,5-OXATHIADIAZOL-4-YL)BIPHENYL) METHYL)-BENZIMIDAZOLE-7-CARBOXYLATE; USE TO TREAT CIRCULATORY DISEASES SUCH AS HYPERTENSIVE DISEASES AND HEART DISEASES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-08-08 | — | — | US | disclosed |
| US-5354766-A | 2-Ethoxy-1-((2'(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl) biphenyl-4-yl)methyl)benzimidazole-7-carboxylic acid; hypotensive agents; CNS activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0520423-A2 | Heterocyclic compounds, their production and use as angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-30 | — | — | EP | disclosed |