Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.46 |
| ▸ | ITGAV | P06756 | 14/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.39 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6801502 | 0.89 | ITGB3 (0.49) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL6771727 | 0.87 | ITGB1 (0.48) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL6768527 | 0.79 | ITGB3 (0.52) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL6774218 | 0.78 | ITGB3 (0.47) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL6769604 | 0.77 | ITGB3 (0.47) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL6772892 | 0.77 | ITGB3 (0.51) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL6768513 | 0.76 | ITGB3 (0.56) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL6773136 | 0.75 | ITGB3 (0.52) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL6773294 | 0.75 | ITGB3 (0.52) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL6772750 | 0.74 | ITGB3 (0.55) | ITGB3ITGAVITGA2BITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289959-A1 | DIHYDROSTILBENE ALKANOIC ACID DERIVATIVES USEFUL AS VITRONECTIN ANTAGONISTS | Pharmacia Corporation (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096310-A1 | DIHYDROSTILBENE ALKANOIC ACID DERIVATIVES USEFUL AS VITRONECTIN ANTAGONISTS | PHARMACIA CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |