Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.79 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.73 |
| ▸ | F10 | P00742 | 2/20 | 0.73 |
| ▸ | PLG | P00747 | 1/20 | 0.73 |
| ▸ | PLAT | P00750 | 1/20 | 0.73 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.73 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7017283 | 1.00 | F2 (0.79) | F2PRSS1F10PLGPLAT | |
| SCHEMBL7015978 | 0.99 | F2 (0.78) | F2PRSS1F10PLGPLAT | |
| SCHEMBL8488500 | 0.99 | F2 (0.78) | F2PRSS1F10PLGPLAT | |
| SCHEMBL7023038 | 0.96 | F2 (0.73) | F2PRSS1F10PLGPLAT | |
| SCHEMBL8489778 | 0.96 | F2 (0.73) | F2PRSS1F10PLGPLAT | |
| SCHEMBL7020745 | 0.90 | F2 (0.64) | F2PRSS1F10PLGPLAT | |
| SCHEMBL8490042 | 0.90 | F2 (0.64) | F2PRSS1F10PLGPLAT | |
| SCHEMBL7025799 | 0.90 | F2 (0.69) | F2PRSS1F10PLGPLAT | |
| SCHEMBL7025792 | 0.90 | F2 (0.69) | F2PRSS1F10PLGPLAT | |
| SCHEMBL8487625 | 0.90 | F2 (0.64) | F2PRSS1F10PLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739886-B1 | Selective thrombin inhibitors | LG CHEMICAL LTD (KR) | 2003-10-01 | — | — | EP | disclosed |
| US-6284912-B1 | Process for synthesizing para-and/or meta-substituted cyanophenyalanine derivatives | LG CHEMICAL, LTD. (KR) | 2001-09-04 | — | — | US | disclosed |
| EP-1043309-A1 | Process for synthesizing para-and/or meta-substituted cyanophenylalanine derivatives | LG Chemical Ltd. (KR) | 2000-10-11 | — | — | EP | disclosed |
| US-5985899-A | ANTICOAGULANTS | LG CHEMICAL LTD. (KR) | 1999-11-16 | — | — | US | disclosed |
| US-5977114-A | Selective thrombin inhibitors | LG CHEMICAL LTD. (KR) | 1999-11-02 | — | — | US | disclosed |
| US-5747535-A | AMIDINOPHENYL COMPOUNDS | LG CHEMICAL LTD. (KR) | 1998-05-05 | — | — | US | disclosed |
| WO-1997049673-A1 | SELECTIVE THROMBIN INHIBITORS | LG CHEMICAL LTD. (KR) | 1997-12-31 | — | — | WO | disclosed |
| EP-0739886-A2 | Selective thrombin inhibitors | LG Chemical Limited (KR) | 1996-10-30 | — | — | EP | disclosed |