Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 13/20 | 0.43 |
| ▸ | ITGB5 | P18084 | 13/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.43 |
| ▸ | ITGB6 | P18564 | 10/20 | 0.43 |
| ▸ | ITGB8 | P26012 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012379 | 0.87 | ITGAV (0.45) | ITGAVITGB3ITGB5ITGB1ITGB6 | |
| SCHEMBL22893988 | 0.86 | ITGAV (0.46) | ITGAVITGB3ITGB5ITGB1ITGB6 | |
| SCHEMBL30335853 | 0.84 | ITGAV (0.52) | ITGAVITGB3ITGB5ITGB1ITGB6 | |
| SCHEMBL28337171 | 0.82 | ITGAV (0.47) | ITGAVITGB3ITGB5ITGB1ITGB6 | |
| SCHEMBL7017292 | 0.82 | ITGAV (0.45) | ITGAVITGB3ITGB5ITGB1ITGB6 | |
| SCHEMBL7007445 | 0.82 | ITGAV (0.47) | ITGAVITGB3ITGB5ITGB1ITGB6 | |
| SCHEMBL30335954 | 0.82 | ITGAV (0.47) | ITGAVITGB3ITGB5ITGB1ITGB6 | |
| Hydrochloric Acid SCHEMBL20481212 | 0.81 | ITGAV (0.47) | ITGAVITGB3ITGB5ITGB1ITGB6 | |
| SCHEMBL20481236 | 0.80 | ITGAV (0.49) | ITGAVITGB3ITGB5ITGB1ITGB6 | |
| SCHEMBL22008442 | 0.78 | ITGAV (0.51) | ITGAVITGB3ITGB5ITGB1ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946165-B1 | INTEGRIN ANTAGONISTS | MERCK & CO INC (US) | 2003-04-09 | — | — | EP | disclosed |