SCHEMBL70173

SCHEMBL70173

COC(=O)c1cccc(CCc2cccc(C(=O)OC)c2)c1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 3/20 0.83
CYP4A11 Q02928 3/20 0.83
LOXL2 Q9Y4K0 2/20 0.74
SLC7A5 Q01650 1/20 0.62
MRGPRX4 Q96LA9 2/20 0.57
ALDH1A1 P00352 2/20 0.57
HPGD P15428 1/20 0.57
PARP1 P09874 1/20 0.56
KDM4E B2RXH2 1/20 0.56
MAPT P10636 1/20 0.56
RAB9A P51151 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
TSHR P16473 1/20 0.55
HIF1A Q16665 1/20 0.55
FOLH1 Q04609 1/20 0.54
DHODH Q02127 1/20 0.53
MEN1 O00255 1/20 0.52
NPC1 O15118 1/20 0.52
KMT2A Q03164 1/20 0.52
POLB P06746 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1926802 0.95 CYP4F2 (0.76) CYP4F2CYP4A11LOXL2SLC7A5MRGPRX4
SCHEMBL10609527 0.91 CYP4F2 (0.76) CYP4F2CYP4A11LOXL2SLC7A5MRGPRX4
SCHEMBL46931 0.91 CYP4A11 (1.00) CYP4F2CYP4A11LOXL2SLC7A5MRGPRX4
SCHEMBL1696378 0.91 CYP4F2 (0.76) CYP4F2CYP4A11LOXL2SLC7A5MRGPRX4
SCHEMBL6011697 0.90 CYP4F2 (0.73) CYP4F2CYP4A11LOXL2SLC7A5MRGPRX4
SCHEMBL6011695 0.90 CYP4F2 (0.73) CYP4F2CYP4A11LOXL2SLC7A5MRGPRX4
SCHEMBL244703 0.90 CYP4F2 (0.73) CYP4F2CYP4A11LOXL2SLC7A5MRGPRX4
SCHEMBL3012713 0.90 LOXL2 (0.76) CYP4F2CYP4A11LOXL2SLC7A5MRGPRX4
SCHEMBL9522938 0.90 CYP4F2 (0.73) CYP4F2CYP4A11LOXL2SLC7A5MRGPRX4
SCHEMBL5544436 0.90 CYP4F2 (0.73) CYP4F2CYP4A11LOXL2SLC7A5MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-6342504-B1 PEPTIDES AS ANTITHROMBINS AND ANTICOAGULANTS CORVAS INTERNATIONAL, INC. 2002-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 CYP4F2 2876/4885CYP4A11 1392/4885LOXL2 3723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.