Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | PPARA | Q07869 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL700951 | 1.00 | HDAC1 (0.39) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| SCHEMBL15619096 | 1.00 | HDAC1 (0.39) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| SCHEMBL2326465 | 0.89 | CA2 (0.40) | PPARGMAPTSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8911416 | 0.89 | CA2 (0.40) | PPARGMAPTSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5693888 | 0.86 | MAPT (0.47) | MAPTCA2 | |
| SCHEMBL2797629 | 0.85 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL3069494 | 0.85 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL2327079 | 0.85 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL10088095 | 0.84 | CA1 (0.40) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| SCHEMBL14003053 | 0.84 | HTT (0.36) | HDAC1HDAC2CHRM1AKR1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124634-B2 | CB1 receptor modulators | 7TM PHARMA A/S (DK) | 2012-02-28 | — | — | US | disclosed |