SCHEMBL70175

SCHEMBL70175

O=C(O)c1cnn(-c2ccccc2)c1C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
NR4A3 Q92570 1/20 0.61
MAPT P10636 1/20 0.61
KEAP1 Q14145 1/20 0.59
NFE2L2 Q16236 1/20 0.59
MAPK1 P28482 1/20 0.56
RIPK2 O43353 1/20 0.56
MAPK14 Q16539 1/20 0.53
SLC9A1 P19634 1/20 0.48
SLC9A2 Q9UBY0 1/20 0.48
ALDH1A1 P00352 4/20 0.47
HPGD P15428 2/20 0.47
KDM4E B2RXH2 1/20 0.47
PTGS2 P35354 1/20 0.47
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10340610 0.88 RIPK2 (0.64) POLBSMN1; SMN2L3MBTL1NR4A3MAPT
SCHEMBL3262744 0.81 SMN1; SMN2 (0.49) POLBSMN1; SMN2L3MBTL1NR4A3MAPT
SCHEMBL10998196 0.81 POLB (0.61) POLBSMN1; SMN2L3MBTL1NR4A3MAPT
SCHEMBL30700183 0.81 SMN1; SMN2 (0.49) POLBSMN1; SMN2L3MBTL1NR4A3MAPT
SCHEMBL2853100 0.80 POLB (0.64) POLBSMN1; SMN2L3MBTL1NR4A3MAPT
SCHEMBL5067628 0.80 SMN1; SMN2 (0.59) POLBSMN1; SMN2L3MBTL1NR4A3MAPT
SCHEMBL20027934 0.80 MAPT (0.51) POLBSMN1; SMN2L3MBTL1NR4A3MAPT
SCHEMBL1335080 0.80 RIPK2 (0.78) POLBSMN1; SMN2L3MBTL1NR4A3MAPT
SCHEMBL20027644 0.80 NPC1 (0.57) POLBSMN1; SMN2L3MBTL1NR4A3MAPT
SCHEMBL3076270 0.80 MAPT (0.59) POLBSMN1; SMN2L3MBTL1NR4A3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-4801326-A PRODUCTION OF HYBRID SEED ELI LILLY AND COMPANY (US) 1989-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 POLB 3973/4885SMN1; SMN2 4357/4885L3MBTL1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.