Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.48 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783060 | 0.86 | MAPK1 (0.71) | POLBSMN1; SMN2L3MBTL1NR4A3MAPT | |
| SCHEMBL2872595 | 0.84 | PTPN1 (0.50) | POLBSMN1; SMN2L3MBTL1NR4A3MAPT | |
| SCHEMBL4578766 | 0.82 | RIPK2 (0.49) | POLBSMN1; SMN2L3MBTL1NR4A3MAPT | |
| SCHEMBL70175 | 0.81 | POLB (0.61) | POLBSMN1; SMN2L3MBTL1NR4A3MAPT | |
| SCHEMBL3076270 | 0.80 | MAPT (0.59) | POLBSMN1; SMN2L3MBTL1NR4A3MAPT | |
| SCHEMBL5067628 | 0.80 | SMN1; SMN2 (0.59) | POLBSMN1; SMN2L3MBTL1NR4A3MAPT | |
| SCHEMBL27405 | 0.80 | MAPK1 (0.78) | POLBSMN1; SMN2L3MBTL1NR4A3MAPT | |
| SCHEMBL2853100 | 0.80 | POLB (0.64) | POLBSMN1; SMN2L3MBTL1NR4A3MAPT | |
| SCHEMBL1335080 | 0.80 | RIPK2 (0.78) | POLBSMN1; SMN2L3MBTL1NR4A3MAPT | |
| Hydrochloric Acid SCHEMBL3517693 | 0.79 | RIPK2 (0.76) | POLBSMN1; SMN2L3MBTL1NR4A3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4537886-A | β-lactam antibacterial agents and compositions containing them | BEECHAM GROUP P.L.C. (GB) | 1985-08-27 | — | — | US | disclosed |
| EP-0090656-A1 | Penicillins, a process for the preparation and compositions containing them | BEECHAM GROUP PLC (GB) | 1983-10-05 | — | — | EP | disclosed |