Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012036 | 0.90 | ZAP70 (0.32) | EP300CREBBPHTR2CSLC6A4 | |
| SCHEMBL7016126 | 0.84 | NPY1R (0.33) | NPY1RKCNH2 | |
| SCHEMBL7015911 | 0.84 | NPY1R (0.35) | NPY1RKCNH2 | |
| SCHEMBL7018069 | 0.82 | HTR2C (0.31) | HTR2CSLC6A4 | |
| SCHEMBL7015649 | 0.81 | NPY1R (0.61) | NPY1RKCNH2 | |
| SCHEMBL7015313 | 0.80 | PIK3C2B (0.34) | KCNH2EP300CREBBPHTR2CSLC6A4 | |
| SCHEMBL7011740 | 0.80 | CASR (0.36) | NPY1RKCNH2 | |
| SCHEMBL7016776 | 0.79 | CASR (0.35) | NPY1RKCNH2 | |
| SCHEMBL7016912 | 0.79 | HTR2C (0.35) | HTR2CSLC6A4 | |
| SCHEMBL7011382 | 0.79 | JAK3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |