Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 7/20 | 0.35 |
| ▸ | NPY1R | P25929 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 4/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011740 | 0.93 | CASR (0.36) | CASRNPY1RKCNH2SPHK1EGFR | |
| SCHEMBL7016255 | 0.83 | ALDH1A1 (0.34) | MAPTSMN1; SMN2 | |
| SCHEMBL7017114 | 0.81 | CASR (0.37) | CASRNPY1RKCNH2SPHK1EGFR | |
| SCHEMBL7017580 | 0.79 | NPY1R (0.37) | NPY1RKCNH2 | |
| SCHEMBL7012036 | 0.77 | ZAP70 (0.32) | — | |
| SCHEMBL7016596 | 0.77 | NPY1R (0.34) | CASRNPY1RKCNH2 | |
| SCHEMBL7012030 | 0.77 | NPY1R (0.34) | CASRNPY1RKCNH2 | |
| SCHEMBL7011470 | 0.77 | NPY1R (0.35) | CASRNPY1RKCNH2SPHK1 | |
| SCHEMBL7011382 | 0.73 | JAK3 (0.39) | NPC1MAPTRAB9ASMN1; SMN2AKT1 | |
| SCHEMBL7011391 | 0.73 | JAK2 (0.36) | NPY1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |