Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7017612 | 1.00 | NPC1 (0.33) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7021550 | 0.92 | RAB9A (0.36) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7021553 | 0.92 | RAB9A (0.36) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7020246 | 0.92 | NPC1 (0.32) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7020249 | 0.92 | NPC1 (0.32) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7026490 | 0.91 | RAB9A (0.35) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7026484 | 0.91 | RAB9A (0.35) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7025912 | 0.91 | NPC1 (0.33) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7025921 | 0.91 | NPC1 (0.33) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7028561 | 0.90 | RAB9A (0.36) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929509-B1 | LIQUID CRYSTAL ALKENYL BICYCLO 2.2.2]OCTANES AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS | QINETIQ LTD (GB) | 2003-01-15 | — | — | EP | disclosed |
| US-6187393-B1 | FOR LIQUID CRYSTAL DISPLAYS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 2001-02-13 | — | — | US | disclosed |