Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 14/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL586063 | 0.87 | FFAR1 (0.58) | FFAR1FFAR4KEAP1 | |
| SCHEMBL4715187 | 0.85 | MEN1 (0.57) | MEN1KMT2ASLC22A12 | |
| SCHEMBL7015990 | 0.80 | FFAR1 (0.51) | FFAR1FFAR4KEAP1 | |
| SCHEMBL30444612 | 0.78 | FFAR1 (0.65) | FFAR1FFAR4S1PR1KEAP1 | |
| SCHEMBL4715830 | 0.78 | S1PR1 (0.58) | FFAR1FFAR4S1PR1SLC22A12KEAP1 | |
| SCHEMBL6985623 | 0.78 | FFAR1 (0.65) | FFAR1FFAR4S1PR1KEAP1 | |
| SCHEMBL6954266 | 0.77 | CYP1A2 (0.57) | FFAR1FFAR4 | |
| Phenyl Propionic Acid SCHEMBL6691396 | 0.77 | KEAP1 (0.70) | FFAR1FFAR4MEN1KMT2AKEAP1 | |
| SCHEMBL7020238 | 0.76 | FFAR1 (0.66) | FFAR1FFAR4S1PR1KEAP1 | |
| Hydrochloric Acid SCHEMBL7358774 | 0.76 | CYP1A2 (0.56) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337517-A1 | PYRIMIDINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002030911-A1 | PYRIMIDINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-04-18 | — | — | WO | disclosed |