Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 10/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7026301 | 0.99 | TSHR (0.43) | TSHRTPSAB1F2F7F3 | |
| SCHEMBL7027219 | 0.93 | TPSAB1 (0.41) | TSHRTPSAB1F2F7F3 | |
| SCHEMBL7027846 | 0.91 | TSHR (0.42) | TSHRTPSAB1F2F7F3 | |
| SCHEMBL7020326 | 0.88 | TPSAB1 (0.43) | TSHRTPSAB1F2F7F3 | |
| SCHEMBL7027708 | 0.88 | TPSAB1 (0.43) | TSHRTPSAB1F2F7F3 | |
| SCHEMBL7018545 | 0.86 | TPSAB1 (0.43) | TSHRTPSAB1F2F7F3 | |
| SCHEMBL7021757 | 0.86 | TPSAB1 (0.42) | TSHRTPSAB1F2F7F3 | |
| SCHEMBL7029085 | 0.86 | TPSAB1 (0.43) | TSHRTPSAB1F2F7F3 | |
| SCHEMBL7020466 | 0.86 | TPSAB1 (0.43) | TSHRTPSAB1F2F7F3 | |
| SCHEMBL7021799 | 0.85 | TPSAB1 (0.43) | TSHRTPSAB1F2F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |