SCHEMBL7017916

SCHEMBL7017916

CCCNC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc(SC)c2OC(=O)OCC)cc1

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 7/20 0.73
AGTR1 P30556 4/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7706786 0.96 AGTR2 (0.75) AGTR2AGTR1
SCHEMBL7026032 0.95 AGTR2 (0.66) AGTR2AGTR1
SCHEMBL7021275 0.92 AGTR2 (0.79) AGTR2AGTR1
SCHEMBL7019431 0.92 AGTR2 (0.63) AGTR2AGTR1
SCHEMBL9565172 0.91 AGTR2 (0.61) AGTR2AGTR1
SCHEMBL7101649 0.91 AGTR2 (0.71) AGTR2AGTR1
SCHEMBL7022811 0.90 AGTR2 (0.60) AGTR2AGTR1
SCHEMBL7026311 0.90 AGTR2 (0.62) AGTR2AGTR1
SCHEMBL7021152 0.89 AGTR2 (0.58) AGTR2AGTR1
SCHEMBL8899395 0.88 AGTR2 (0.83) AGTR2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0560177-B1 Imidazole derivatives having biphenylsulphonylurea or biphenylsulfonylurethane side chains, process for their production and use thereof HOECHST AG (DE) 2003-01-08 EP disclosed
EP-0577023-A2 Angiotensin-II receptor-antagonists for the treatment of arrhythmices HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-05 EP disclosed
EP-0577025-A2 Angiotensin-II-receptorantagonist for the treatment and prophylaxis of coronary heart diseases HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-05 EP disclosed
EP-0560177-A1 Imidazole derivatives having biphenylsulphonylurea or biphenylsulfonylurethane side chains, process for their production and use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1993-09-15 EP disclosed