Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30339621 | 0.74 | TP53 (0.41) | TP53MEN1PABPC1KMT2APOLB | |
| SCHEMBL8830969 | 0.74 | TP53 (0.41) | TP53MEN1PABPC1KMT2APOLB | |
| SCHEMBL18726784 | 0.74 | TP53 (0.41) | TP53MEN1PABPC1KMT2APOLB | |
| SCHEMBL5317523 | 0.74 | TP53 (0.41) | TP53MEN1PABPC1KMT2APOLB | |
| SCHEMBL84705 | 0.74 | GRM5 (0.46) | TP53MEN1PABPC1KMT2APOLB | |
| SCHEMBL25468618 | 0.74 | TP53 (0.41) | TP53MEN1PABPC1KMT2APOLB | |
| SCHEMBL1186947 | 0.72 | KDM4E (0.38) | TP53MEN1KMT2ADAOALDH1A1 | |
| SCHEMBL30814447 | 0.72 | KMT2A (0.50) | TP53MEN1PABPC1KMT2APOLB | |
| SCHEMBL2715939 | 0.72 | KMT2A (0.50) | TP53MEN1PABPC1KMT2APOLB | |
| SCHEMBL12759469 | 0.72 | POLB (0.66) | TP53POLBALDH1A1MAPTPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915224-B2 | Method of preparing peptide | AJINOMOTO CO., INC. (JP) | 2011-03-29 | — | — | US | disclosed |
| EP-0662078-B1 | REAGENTS FOR PEPTIDE COUPLINGS | RES CORP TECHNOLOGIES INC (US) | 2003-05-02 | — | — | EP | disclosed |
| US-RE38073-E1 | Biosynthesis; using dehydration agent | RESEARCH CORPORATIONS TECHNOLOGIES, INC. | 2003-04-08 | — | — | US | disclosed |
| US-6534627-B1 | Using FMOC (9-fluorenylmethyloxycarbonyl) and tert-butyl containing compounds as protecting group; efficiency and storage stability | RESEARCH CORPORATION TECNOLOGIES, INC. | 2003-03-18 | — | — | US | disclosed |
| US-RE37686-E1 | Azahydroxybenzotriazoles and derivatives thereof for peptide coupling reactions | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2002-04-30 | — | — | US | disclosed |
| US-6040422-A | REACTING A FLUOROFORMAMIDINIUM SALT WITH AN N-AMINO PROTECTED, OPTIONALLY SIDE CHAIN PROTECTED AMINO ACID; THEN REACTING PRODUCT WITH A CARBOXY PROTECTED AMINO ACID; FOR COMPOUNDS WITH LONG TERM STORAGE STABILITY | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2000-03-21 | — | — | US | disclosed |
| US-5750767-A | REACTING PROTECTED AMINO ACID WITH FLUOROFORMAMIDINIUM SALT | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1998-05-12 | — | — | US | disclosed |
| US-5712418-A | FLUOROFORMAMIDINIUM SALTS AS FLUORINATION AGENTS TO FORM PEPTIDES | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1998-01-27 | — | — | US | disclosed |
| US-5698675-A | AMIDATION; ESTERIFICATION | RESEARCH CORPORATION TECH., INC. (US) | 1997-12-16 | — | — | US | disclosed |
| US-5644029-A | TRIAZOLO-PYRIDINE HETEROCYCLIC COMPOUNDS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5580981-A | YELLOW INDICATORS FADING TO COLORLESS UPON COMPLETION OF THE ACYLATION STEP IN AMIDE FORMATION; REACTION ACCELERATORS; LOWERS RACEMIZATION | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1996-12-03 | — | — | US | disclosed |
| WO-1996004297-A9 | SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS | — | 1996-05-02 | — | — | WO | disclosed |
| WO-1996004297-A1 | SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1996-02-15 | — | — | WO | disclosed |
| EP-0662078-A1 | NEW REAGENTS FOR PEPTIDE COUPLINGS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-07-12 | — | — | EP | disclosed |
| WO-1994007910-A1 | NEW REAGENTS FOR PEPTIDE COUPLINGS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-04-14 | — | — | WO | disclosed |