SCHEMBL84705

SCHEMBL84705

Cn1cnc2cccnc21

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 2/20 0.46
DYRK1A Q13627 1/20 0.41
ACVR1 Q04771 1/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
PABPC1 P11940 1/20 0.41
KMT2A Q03164 1/20 0.41
PDE4A P27815 2/20 0.39
PDE4B Q07343 2/20 0.39
PDE4C Q08493 2/20 0.39
PDE4D Q08499 2/20 0.39
ALDH1A1 P00352 1/20 0.38
HRH4 Q9H3N8 1/20 0.38
NSD3 Q9BZ95 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30339621 0.74 TP53 (0.41) MEN1TP53PABPC1KMT2AALDH1A1
SCHEMBL7017923 0.74 TP53 (0.44) MEN1TP53PABPC1KMT2AALDH1A1
SCHEMBL18726784 0.74 TP53 (0.41) MEN1TP53PABPC1KMT2AALDH1A1
SCHEMBL5317523 0.74 TP53 (0.41) MEN1TP53PABPC1KMT2AALDH1A1
SCHEMBL8830969 0.74 TP53 (0.41) MEN1TP53PABPC1KMT2AALDH1A1
SCHEMBL25468618 0.74 TP53 (0.41) MEN1TP53PABPC1KMT2AALDH1A1
SCHEMBL23228232 0.74 TP53 (0.38) MEN1TP53PABPC1KMT2AALDH1A1
SCHEMBL1106478 0.74 PDE4A (0.43) DYRK1AMEN1TP53PABPC1KMT2A
SCHEMBL24198356 0.74 TP53 (0.38) MEN1TP53PABPC1KMT2AALDH1A1
SCHEMBL8970101 0.74 MEN1 (0.51) DYRK1AMEN1TP53PABPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 358 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5084453-A Antibiotics, bactericides BANYU PHARMACEUTICAL CO., LTD. (JP) 1992-01-28 US claimed
JP-9202774-A None JP disclosed
CN-122011353-A Imidazopyridine catalyst for liquid crystal polyarylester synthesis and application thereof 浙江海利得科技有限公司 2026-05-12 CN disclosed
US-20240327410-A1 Monoacylglycerol Lipase Modulators JANSSEN PHARMACEUTICA NV (BE) 2024-10-03 US disclosed
US-11993601-B2 Monoacylglycerol lipase modulators JANSSEN PHARMACEUTICA NV 2024-05-28 US disclosed
WO-2024105364-A1 HETEROCYCLIC INHIBITORS OF CDC-LIKE KINASES CURADEV PHARMA LTD (GB) 2024-05-23 WO disclosed
US-20240066047-A1 ANTIBODY-DRUG CONJUGATES COMPRISING A CYCLIC DINUCLEOTIDE TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-02-29 US disclosed
WO-2023212549-A1 TRICYCLIC PYRIDONES AND PYRIMIDONES ERASCA, INC. (US) 2023-11-02 WO disclosed
US-20230338341-A1 SUBSTITUTED 1H-IMIDAZO[4,5-b]PYRIDIN-2(3H)-ONES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2023-10-26 US disclosed
US-20230312605-A1 PYRROLO[2,1-F][1,2,4]TRIAZINES AND PREPARATION AND USES THEREOF TENARX, INC. 2023-10-05 US disclosed
WO-2006107784-A1 IMIDAZOPYRIDAZINE COMPOUNDS ELI LILLY AND COMPANY (US) 2006-10-12 WO disclosed
US-6875765-B2 Arylsulfonamide ethers, and methods of use thereof WARNER-LAMBERT COMPANY (US) 2005-04-05 US disclosed
US-6096758-A 3-METHYLIMIDAZOPYRIDINES USED FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 2000-08-01 US disclosed
US-6096758-A 3-METHYLIMIDAZOPYRIDINES USED FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 2000-08-01 US disclosed
EP-0882048-A1 3-METHYLIMIDAZOPYRIDINES Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1998-12-09 EP disclosed
US-5723468-A COGNITION ACTIVATORS FOR MEMOY LOSS AMERICAN HOME PRODUCTS CORPORATION (US) 1998-03-03 US disclosed
JP-H09202774-A 2-ARYLQUINOLINE AND ITS PRODUCTION GREEN CROSS CORP:THE 1997-08-05 JP disclosed
WO-1997027192-A1 3-METHYLIMIDAZOPYRIDINES BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1997-07-31 WO disclosed
EP-0786460-A2 2-Arylquinolines and process for producing the same ASAHI GLASS COMPANY LTD. (JP) 1997-07-30 EP disclosed
US-5571819-A Imidazopyridines as muscarinic agents WYETH 1996-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240066047-A1 ANTIBODY-DRUG CONJUGATES COMPRISING A CYCLIC DINUCLEOTIDE STING1, TLR9, CGAS GRM5 1246/4885DYRK1A 3696/4885ACVR1 2616/4885
US-11993601-B2 Monoacylglycerol lipase modulators MGLL, LPL, PNLIP GRM5 130/4885DYRK1A 3616/4885ACVR1 4669/4885
US-20230312605-A1 PYRROLO[2,1-F][1,2,4]TRIAZINES AND PREPARATION AND USES THEREOF DYRK1A, DYRK2, DYRK1B GRM5 1655/4885DYRK1A 1/4885ACVR1 1564/4885
US-20240327410-A1 Monoacylglycerol Lipase Modulators MGLL, LPL, PNLIP GRM5 130/4885DYRK1A 3616/4885ACVR1 4669/4885
US-20230338341-A1 SUBSTITUTED 1H-IMIDAZO[4,5-b]PYRIDIN-2(3H)-ONES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS GRIN2B, GRIN2A, GRIN2C GRM5 21/4885DYRK1A 1746/4885ACVR1 1861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.