Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7018210 | 0.82 | F10 (0.47) | F10SMN1; SMN2DUSP3PTPN5PTPN11 | |
| SCHEMBL7016375 | 0.79 | F10 (0.71) | F10 | |
| SCHEMBL7017231 | 0.73 | F10 (0.45) | F10 | |
| SCHEMBL15297743 | 0.72 | GPR119 (0.43) | SMN1; SMN2MEN1KMT2AALDH1A1GPR119 | |
| SCHEMBL7011037 | 0.72 | F10 (0.59) | F10MEN1KMT2A | |
| SCHEMBL22999796 | 0.70 | EPHX1 (0.42) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7020200 | 0.69 | F10 (0.44) | F10 | |
| SCHEMBL4712413 | 0.68 | MEN1 (0.48) | SMN1; SMN2DUSP3PTPN5PTPN11TP53 | |
| SCHEMBL17271864 | 0.68 | GPR119 (0.45) | SMN1; SMN2MEN1KMT2AALDH1A1GPR119 | |
| SCHEMBL18143022 | 0.67 | HTR2A (0.52) | MEN1KMT2AALDH1A1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1302462-A1 | SULFONE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-04-16 | — | — | EP | disclosed |