Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 20/20 | 0.76 |
| ▸ | ABL1 | P00519 | 1/20 | 0.76 |
| ▸ | BCR | P11274 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3232019 | 0.88 | SRC (0.86) | SRCABL1BCR | |
| SCHEMBL5255444 | 0.87 | SRC (0.77) | SRCABL1BCR | |
| SCHEMBL22206729 | 0.87 | SRC (0.77) | SRCABL1BCR | |
| SCHEMBL3229238 | 0.87 | SRC (1.00) | SRCABL1BCR | |
| SCHEMBL22861713 | 0.86 | SRC (1.00) | SRCABL1BCR | |
| SCHEMBL3981801 | 0.86 | SRC (0.75) | SRCABL1BCR | |
| SCHEMBL6183535 | 0.86 | SRC (0.75) | SRCABL1BCR | |
| SCHEMBL5253427 | 0.86 | SRC (0.75) | SRCABL1BCR | |
| SCHEMBL4078986 | 0.86 | SRC (0.75) | SRCABL1BCR | |
| SCHEMBL3219474 | 0.85 | SRC (0.79) | SRCABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268431-A1 | 3-CYANOQUINOLINES,3-CYANO-1,6-NAPHTHYRIDINES, AND 3-CYANO-1,7-NAPHTHYRIDINES AS PROTEIN KINASE INHIBITORS | Wyeth (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001072711-A1 | 3-CYANOQUINOLINES,3-CYANO-1,6-NAPHTHYRIDINES, AND 3-CYANO-1,7-NAPHTHYRIDINES AS PROTEIN KINASE INHIBITORS | WYETH (US) | 2001-10-04 | — | — | WO | disclosed |