Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 7/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6793156 | 0.89 | GPR119 (0.50) | STSNAMPTGPR119 | |
| SCHEMBL2796623 | 0.88 | STS (0.67) | STSNAMPTGPR119MEN1KMT2A | |
| SCHEMBL3209950 | 0.85 | STS (0.55) | STSNAMPTGPR119 | |
| SCHEMBL16771053 | 0.85 | STS (0.69) | STSNAMPTGPR119MEN1KMT2A | |
| SCHEMBL18703633 | 0.83 | GPR119 (0.56) | STSNAMPTGPR119 | |
| SCHEMBL7012165 | 0.82 | F10 (0.47) | F10 | |
| SCHEMBL5202414 | 0.82 | STS (0.57) | STSF10 | |
| SCHEMBL17397916 | 0.81 | STS (0.56) | STSNAMPTGPR119 | |
| SCHEMBL5736874 | 0.81 | F10 (0.64) | STSMEN1KMT2AF10 | |
| SCHEMBL28514815 | 0.80 | STS (0.68) | STSNAMPTGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1302462-A1 | SULFONE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | SULT1E1, RRS1, SHH | STS 6/4885NAMPT 4269/4885GPR119 1523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.