Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HTR1D | P28221 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR1F | P30939 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019625 | 0.96 | ALDH1A1 (0.49) | ALDH1A1RECQLNQO2KDM4EHPGD | |
| SCHEMBL7018461 | 0.79 | ALDH1A1 (0.52) | ALDH1A1RECQLNQO2KDM4EHPGD | |
| SCHEMBL13906461 | 0.76 | ALDH1A1 (0.56) | ALDH1A1NQO2KDM4EHPGDHSD17B10 | |
| SCHEMBL7018227 | 0.76 | ALDH1A1 (0.51) | ALDH1A1RECQLKDM4EMAPK1HTT | |
| SCHEMBL11124323 | 0.70 | ALDH1A1 (0.78) | ALDH1A1RECQLKDM4EHPGDMAPT | |
| SCHEMBL5365451 | 0.70 | ALDH1A1 (0.65) | ALDH1A1RECQLKDM4EMAPTLMNA | |
| SCHEMBL6132840 | 0.70 | ALDH1A1 (0.68) | ALDH1A1RECQLKDM4EMAPTLMNA | |
| SCHEMBL16747008 | 0.70 | ALDH1A1 (0.61) | ALDH1A1NQO2KDM4EHPGDHSD17B10 | |
| SCHEMBL6782409 | 0.69 | ALDH1A1 (0.76) | ALDH1A1RECQLKDM4EMAPTLMNA | |
| SCHEMBL9556731 | 0.69 | ALDH1A1 (0.76) | ALDH1A1RECQLKDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038863-B1 | Substituted dimeric compounds, process for their preparation and pharmaceutical compositions thereof | SERVIER LAB (FR) | 2003-06-04 | — | — | EP | claimed |