⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6729019 | 0.72 | — | — | |
| SCHEMBL4307348 | 0.67 | — | — | |
| SCHEMBL34263 | 0.67 | — | — | |
| Bromoacetic Acid SCHEMBL1332313 | 0.67 | — | — | |
| SCHEMBL577017 | 0.67 | — | — | |
| Bromoacetic Acid SCHEMBL7617676 | 0.67 | — | — | |
| SCHEMBL1275692 | 0.67 | — | — | |
| SCHEMBL180158 | 0.67 | — | — | |
| Bromoacetic Acid SCHEMBL1332132 | 0.67 | — | — | |
| Bromoacetic Acid SCHEMBL1332022 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200190513-A1 | METHODS AND SYSTEMS FOR ANALYZING GUIDE RNA MOLECULES | EDITAS MEDICINE, INC. (US) | 2020-06-18 | — | — | US | claimed |
| EP-3615672-A1 | METHODS AND SYSTEMS FOR ANALYZING GUIDE RNA MOLECULES | Editas Medicine, Inc. (US) | 2020-03-04 | — | — | EP | claimed |
| EP-3565895-A1 | SYNTHETIC GUIDE MOLECULES, COMPOSITIONS AND METHODS RELATING THERETO | Editas Medicine, Inc. (US) | 2019-11-13 | — | — | EP | claimed |
| WO-2018201086-A1 | METHODS AND SYSTEMS FOR ANALYZING GUIDE RNA MOLECULES | EDITAS MEDICINE, INC. (US) | 2018-11-01 | — | — | WO | claimed |
| WO-2018126176-A1 | SYNTHETIC GUIDE MOLECULES, COMPOSITIONS AND METHODS RELATING THERETO | EDITAS MEDICINE, INC. (US) | 2018-07-05 | — | — | WO | claimed |
| US-20100061984-A1 | COMPOSITIONS AND METHODS FOR MODULATION OF SUPPRESSOR T CELL ACTIVATION | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-03-11 | — | — | US | claimed |
| WO-2007084775-A9 | COMPOSITIONS AND METHODS FOR MODULATION OF SUPPRESSOR T CELL ACTIVATION | UNIV PENNSYLVANIA (US) | 2007-08-30 | — | — | WO | claimed |
| WO-2007084775-A2 | COMPOSITIONS AND METHODS FOR MODULATION OF SUPPRESSOR T CELL ACTIVATION | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-07-26 | — | — | WO | claimed |
| CN-118345072-A | Synthetic guide molecules, compositions, and methods related thereto | 爱迪塔斯医药公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118076728-A | Engineered cells for therapy | 海岸线生物科学公司 | 2024-05-24 | — | — | CN | disclosed |
| WO-2024102860-A1 | ENGINEERED CELLS FOR THERAPY | SHORELINE BIOSCIENCES, INC. (US) | 2024-05-16 | — | — | WO | disclosed |
| EP-4359541-A2 | ENGINEERED CELLS FOR THERAPY | Editas Medicine, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-110249052-B | Synthetic guide molecules, compositions, and methods related thereto | 爱迪塔斯医药公司 | 2024-04-12 | — | — | CN | disclosed |
| US-20240117383-A1 | SELECTION BY ESSENTIAL-GENE KNOCK-IN | EDITAS MEDICINE, INC. | 2024-04-11 | — | — | US | disclosed |
| EP-0376801-A2 | Polyfluoroalkyl-substituted acetates, thioacetates and acetamides, their preparation and uses | ELF ATOCHEM S.A. (FR) | 1990-07-04 | — | — | EP | disclosed |
| US-4692442-A | ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1987-09-08 | — | — | US | disclosed |
| EP-0094304-A1 | Process for the preparation of cyclopropanecarboxylic-acid derivatives, and intermediates therefor | ROUSSEL-UCLAF (FR) | 1983-11-16 | — | — | EP | disclosed |
| EP-0000645-B1 | ISOPENICILLINS, PROCESSES FOR THEIR PREPARATION, AND COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1981-01-28 | — | — | EP | disclosed |
| EP-0000645-A1 | Isopenicillins, processes for their preparation, and compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1979-02-07 | — | — | EP | disclosed |
| US-4122086-A | Isopenicillins | SMITHKLINE CORPORATION (US) | 1978-10-24 | — | — | US | disclosed |