⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL228965 | 0.79 | — | — | |
| SCHEMBL11286980 | 0.74 | FAAH (0.48) | — | |
| SCHEMBL10777713 | 0.74 | FAAH (0.54) | — | |
| Dihydroxyacetone SCHEMBL70 | 0.74 | — | — | |
| Dihydroxyacetone SCHEMBL2555249 | 0.74 | OR51E2 (0.40) | — | |
| SCHEMBL2706065 | 0.72 | — | — | |
| SCHEMBL14168783 | 0.72 | FAAH (0.58) | — | |
| SCHEMBL538257 | 0.72 | — | — | |
| SCHEMBL10780606 | 0.72 | FAAH (0.58) | — | |
| Dihydroxyacetone SCHEMBL29350199 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655477-A | Synthesis process of propranolol | 江苏福瑞康泰药业有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-116655477-B | Propranolol Synthesis process of Er | 江苏阿尔法集团福瑞药业(宿迁)有限公司 | 2025-07-04 | — | — | CN | disclosed |
| CN-116655477-A | Synthesis process of propranolol | 江苏福瑞康泰药业有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-116655477-A | Synthesis process of propranolol | 江苏福瑞康泰药业有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-110023290-B | Heteroaryl carboxamide compounds as RIPK2 inhibitors | 勃林格殷格翰国际有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-108064224-B | Amide-substituted thiazoles as modulators of Ror gamma t | 詹森药业有限公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-114174293-A | 4- (imidazo [1,2-a ] pyridin-3-yl) -pyrimidine derivatives | 默克专利股份公司 | 2022-03-11 | — | — | CN | disclosed |
| WO-2021179274-A1 | ErbB RECEPTOR INHIBITORS AS ANTI-TUMOR AGENTS | SUZHOU ZANRONG PHARMA LTD. (CN) | 2021-09-16 | — | — | WO | disclosed |
| CN-112979630-A | Trifluoromethanols as Ror gamma t modulators | 詹森药业有限公司 | 2021-06-18 | — | — | CN | disclosed |
| EP-3354651-B1 | TRIFLUOROMETHYL ALCOHOLS AS MODULATORS OF ROR-GAMMA-T | JANSSEN PHARMACEUTICA NV (BE) | 2021-01-06 | — | — | EP | disclosed |
| WO-2007084391-A2 | THIAZOLE COMPOUNDS AS PROTEIN KINASE B ( PKB) INHIBITORS | AMGEN INC. (US) | 2007-07-26 | — | — | WO | disclosed |
| US-20070173506-A1 | Thiazole compounds and methods of use | AMGEN INC. (US) | 2007-07-26 | — | — | US | disclosed |
| US-6811990-B1 | RAPID/FLEXIBLE MEASUREMENT OF CELL CYTOTOXICITY AND/OR PROLIFERATION; ENZYMATIC ACTIVITY COUPLED TO PRODUCTION OF HIGH-ENERGY MOLECULE (ATP) WHICH SERVES AS A SUBSTRATE FOR ILLUMINATION BY A LUCIFERASE; PHOSPHATASES | Corey, Michael J. | 2004-11-02 | — | — | US | disclosed |
| US-20040214881-A1 | Method for producing optically active halopropanediol derivative | KANEKA CORPORATION (JP) | 2004-10-28 | — | — | US | disclosed |
| EP-1422213-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE HALOPROPANEDIOL DERIVATIVE | KANEKA CORPORATION (JP) | 2004-05-26 | — | — | EP | disclosed |
| EP-0313458-B1 | IMIDAZO(2,1-B)BENZOTHIAZOLES AND THEIR ACID ADDITION SALTS, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-08-11 | — | — | EP | disclosed |
| US-4895863-A | MEMORY DISORDERS | ROUSSEL UCLAF (FR) | 1990-01-23 | — | — | US | disclosed |
| EP-0313458-A2 | Imidazo(2,1-b)benzothiazoles and their acid addition salts, process and intermediates for their preparation, their use as medicaments and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1989-04-26 | — | — | EP | disclosed |
| US-4053608-A | 3-NITROPYRIDINE CARBOXAMIDES, POULTRY FEED | SANKYO COMPANY LIMITED (JA) | 1977-10-11 | — | — | US | disclosed |
| US-4028356-A | Triazinobenzodiazepines | THE UPJOHN COMPANY (US) | 1977-06-07 | — | — | US | disclosed |